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Mood disorder studies

Mood disorders cover a wide range of difficulties, including but not limited to:

  • Bipolar Disorder
  • Cyclothymia
  • Depression (all types)
  • Disruptive Mood Dysregulation
  • Hypomania Disorder
  • Premenstrual Dysphoric Disorder​

Current related studies open for recruitment

Summary

To understand the causes of depression and anxiety and to develop new treatments. Recruiting a large number of participants who will provide responses to a comprehensive set of questions. The participants will be recruited into an existing biobank, the NIHR BioResource for Translational Research in Common and Rare Diseases, a recontactable biobank.

Inclusion criteria

​​1. Participants who may have suffered or have been diagnosed with depression or anxiety.

2. Participants who are aged 16 or over.

3. Participants who have not stated their refusal to take part in future research.​

Exclusion criteria

1. Individual without the capacity to provide informed consent.

2. Individuals under the age of 16 years.

3. Individuals who do not have a current diagnosis of who do not meet the screening criteria for a lifetime DSM-5 diagnosis of depression or anxiety.​

Targeted, end date and PI

​EPUT: 350

01.09.28

PI: Ms Nicola Armstrong 

Study Lead: Elizabeth Phillips​​

Summary

​To investigate if genetic profiling can help optimise the prescribing of psychotropic medications, and lead to improved clinical outcomes and reduced side effects. Participants who consent to take part in the study will be offered genome-wide genotyping. To recruit adult patients with schizophrenia, delusional, schizophrenic or bipolar disorders. Hospital ward- or community centre-based initial assessment if the participant is an outpatient. Follow-up assessments can occur on the ward or in the community if the patient has been discharged. Final follow-up is based on clinical record.

Inclusion criteria

​1. Patients aged 18+.

2. Men or women.

3. With an ICD10 diagnosis of any “mental, behavioural or neurodevelopmental disorders”, Codes F01 – F99.​​

Exclusion criteria

​​1. Patients with current high risks of self-harm or harm to others.

2. Patients who lack capacity to consent to taking part in the research.​​​

Targeted, end date and PI

EPUT: 45

13.04.25

PI: Dr Shaimaa Aboelenien 

Study Lead: Natalie Rodney​